Studied: The antiobesity effect of germinated waxy black rice

Black rice is healthier than white rice as it contains more antioxidants, proteins, and dietary fiber, and less sugar. A study published in the Journal of Medicinal Food investigated the effect of supplementing with germinated waxy black rice (GWBR) on mice with high-fat-diet-induced obesity.

  • The researchers divided the mice into four groups:
    • Normal diet (ND)
    • High-fat diet (HFD)
    • Test group supplemented with 2.5 percent GWBR
    • Test group supplemented with 5 percent GWBR
  • Supplementation with GBR reduced body weight gain and lipid accumulation in the liver and adipose tissue compared to the control group given the high-fat diet.
  • GWBR also reduced triglyceride (TG), total cholesterol, and low-density lipoprotein cholesterol levels in serum while increasing high-density lipoprotein cholesterol levels.
  • The mRNA levels of transcriptional factors, peroxisome proliferator-activated receptor-gamma, CCAAT enhancer-binding protein (C/EBP)-alpha, C/EBP-beta, sterol regulatory element-binding protein-1c, and related genes, including adipocyte fatty acid-binding protein, fatty acid synthase, and lipoprotein lipase, were observed to have been markedly lowered in the GWBR groups.
  • On the other hand, lipolytic enzymes, such as hormone-sensitive lipase, adipose TG lipase, and carnitine palmitoyltransferase-1, and uncoupling protein 2 mRNA levels were considerably higher in the animals that received supplementation with GWBR.

The researchers concluded that germinated waxy black rice has anti-obesity effects that decrease the accumulation of fat and promote lipolysis in mice with HFD-induced obesity.

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Journal Reference:

Lim WC, Ho JN, Lee HS, Cho HY. GERMINATED WAXY BLACK RICE SUPPRESSES WEIGHT GAIN IN HIGH-FAT DIET-INDUCED OBESE MICE. Journal of Medicinal Food. 2016;19(4):410–417. DOI: 10.1089/jmf.2015.3590

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